How does TAP pump peptides? insights from DNA repair and traffic ATPases

Immunol Today. 2000 Dec;21(12):598-600. doi: 10.1016/s0167-5699(00)01720-5.

Authors

E A Reits¹, A C Griekspoor, J Neefjes

Affiliation

¹ Dept of Tumor Biology, The Netherlands Cancer Institute, 1066CX, Amsterdam, Netherlands.

PMID: 11114418
DOI: 10.1016/s0167-5699(00)01720-5

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

ATP Binding Cassette Transporter, Subfamily B, Member 2
ATP Binding Cassette Transporter, Subfamily B, Member 3
ATP-Binding Cassette Transporters / chemistry
ATP-Binding Cassette Transporters / metabolism*
Adenosine Triphosphatases / chemistry
Adenosine Triphosphate / pharmacology
Adenosine Triphosphate / physiology*
Allosteric Regulation
Allosteric Site
Antigen Presentation*
Antigens / metabolism*
Binding Sites
DNA Repair
Dimerization
Histocompatibility Antigens Class I / metabolism
Humans
Models, Immunological
Models, Molecular
Protein Binding
Protein Conformation
Protein Structure, Tertiary
Structure-Activity Relationship

Substances

ATP Binding Cassette Transporter, Subfamily B, Member 2
ATP Binding Cassette Transporter, Subfamily B, Member 3
ATP-Binding Cassette Transporters
Antigens
Histocompatibility Antigens Class I
TAP1 protein, human
TAP2 protein, human
Adenosine Triphosphate
Adenosine Triphosphatases