Ultrasound-guided fine-needle aspiration and thyroid disease

Otolaryngol Head Neck Surg. 2000 Dec;123(6):700-5. doi: 10.1067/mhn.2000.110958.

Abstract

Background: Fine-needle aspiration represents a critical diagnostic test in determining proper management of thyroid disease and the use of ultrasound-guided fine-needle aspiration (USGFNA) has increased over the years.

Methods: A retrospective chart review of patients undergoing USGFNA. Two hundred fifteen patients underwent 234 procedures with 362 nodules aspirated within a 2 (1/2)-year period.

Results: The mean ages of women and men were 51.9 and 57.8, respectively. The average size of nodules was 2.1 cm. A difficult to assess gland or nodule was the most common indication for USGFNA (33%). The sensitivity was 88.2%, specificity was 80.0%, the PPV was 65.2%, the negative predictive value was 94.1%, and the accuracy was 82.5%. The cancer yield, inadequacy, and complication rates were 44%, 10.5%, and 8.5%, respectively.

Conclusions: USGFNA aspiration is a safe and effective diagnostic modality in the management of thyroid disease, especially for nodules that are difficult to palpate.

Publication types

  • Validation Study

MeSH terms

  • Biopsy, Needle / adverse effects
  • Biopsy, Needle / economics
  • Biopsy, Needle / methods*
  • False Negative Reactions
  • False Positive Reactions
  • Female
  • Histological Techniques
  • Humans
  • Male
  • Middle Aged
  • Palpation
  • Patient Selection
  • Retrospective Studies
  • Sensitivity and Specificity
  • Thyroid Diseases / diagnostic imaging*
  • Thyroid Diseases / pathology*
  • Thyroid Diseases / therapy
  • Ultrasonography, Interventional / adverse effects
  • Ultrasonography, Interventional / economics
  • Ultrasonography, Interventional / methods*