Xanthoepocin, a new antibiotic from Penicillium simplicissimum IFO5762

J Antibiot (Tokyo). 2000 Sep;53(9):928-33. doi: 10.7164/antibiotics.53.928.

Abstract

A new antifungal antibiotic xanthoepocin was isolated from the culture broth of Penicillium simplicissimum IFO5762. Xanthoepocin was obtained from the culture fluid by solvent extraction and chromatographic purification. It showed antibiotic activity against Gram-positive bacteria and yeasts.

MeSH terms

  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / isolation & purification*
  • Anti-Bacterial Agents / pharmacology
  • Epoxy Compounds / chemistry
  • Epoxy Compounds / isolation & purification*
  • Epoxy Compounds / pharmacology
  • Gram-Negative Bacteria / drug effects*
  • Magnetic Resonance Spectroscopy
  • Microbial Sensitivity Tests
  • Molecular Conformation
  • Penicillium / chemistry*
  • Penicillium / metabolism
  • Pyrones / chemistry
  • Pyrones / isolation & purification*
  • Pyrones / pharmacology

Substances

  • Anti-Bacterial Agents
  • Epoxy Compounds
  • Pyrones
  • Xanthoepocin