Design and characterization of a laser-based instrument with spectroscopic feedback control for treatment of vascular lesions: the "Smart Scalpel"

J Biomed Opt. 2000 Oct;5(4):375-82. doi: 10.1117/1.1289880.

Abstract

To improve the effectiveness of microsurgical techniques, we are developing a semi-autonomous robotic surgical tool (called the "Smart Scalpel") as an alternate approach to treatment of vascular lesions. The device employs optical reflectance spectroscopy as part of a line scan imaging system to identify and selectively target blood vessels in a vascular lesion for thermal treatment with a focused laser beam. Our proof-of-concept reported here presents the design and construction of a prototype instrument, initial quantification of imaging system resolution and contrast, and preliminary verification of the imaging and targeting strategies with standard targets and live dermal tissue.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Blood Flow Velocity
  • Equipment Design
  • Lasers*
  • Mice
  • Microsurgery / methods*
  • Monitoring, Intraoperative / methods*
  • Reproducibility of Results
  • Spectrum Analysis / instrumentation*
  • Telangiectasis / diagnosis*
  • Telangiectasis / physiopathology
  • Telangiectasis / surgery
  • Vascular Surgical Procedures / methods*