Amiodarone-related optic neuropathy

Jpn J Ophthalmol. 2000 Sep-Oct;44(5):565-8. doi: 10.1016/s0021-5155(00)00216-1.

Abstract

Background: To evaluate a case of atypical optic neuropathy that presented with blurred vision following the use of an antiarrythmic agent.

Case: Record of the patient was reviewed to determine the etiology of his optic neuropathy.

Observations: Ophthalmological examination revealed unilateral optic disc edema with relatively well-preserved visual acuity. In routine tests, results of complete blood count, erythrocyte sedimentation rate, liver and kidney function tests, chest x-ray, Goldmann visual field examination, and brain computed tomography scan were normal. Orbital ultrasonography revealed optic disc edema with prominent optic nerve head and without orbital pathology.

Conclusions: Systemic history and drug intake should be investigated in every patient with optic disc edema. Discontinuation of the medication can prevent further optic nerve damage or involvement of the other eye.

Publication types

  • Case Reports

MeSH terms

  • Amiodarone / adverse effects*
  • Anti-Arrhythmia Agents / adverse effects*
  • Atrial Flutter / drug therapy
  • Diagnosis, Differential
  • Fluorescein Angiography
  • Fundus Oculi
  • Humans
  • Male
  • Middle Aged
  • Optic Disk / diagnostic imaging
  • Optic Disk / pathology
  • Papilledema / chemically induced*
  • Papilledema / diagnosis
  • Ultrasonography
  • Visual Acuity
  • Visual Field Tests
  • Visual Fields

Substances

  • Anti-Arrhythmia Agents
  • Amiodarone