The effect of pupil dilation with tropicamide on vision and driving simulator performance

Eye (Lond). 2000 Jun:14 ( Pt 3A):302-6. doi: 10.1038/eye.2000.77.

Abstract

Purpose: To assess the effect of pupil dilation on vision and driving ability.

Methods: A series of tests on various parameters of visual function and driving simulator performance were performed on 12 healthy drivers, before and after pupil dilation using guttae tropicamide 1%. A driving simulator (Transport Research Laboratory) was used to measure reaction time (RT), speed maintenance and steering accuracy. Tests of basic visual function included high- and low-contrast visual acuity (HCVA and LCVA), Pelli-Robson contrast threshold (CT) and Goldmann perimetry (FIELDS). Useful Field of View (UFOV--a test of visual attention) was also undertaken. The mean differences in the pre- and post-dilatation measurements were tested for statistical significance at the 95% level using one-tail paired t-tests.

Results: Pupillary dilation resulted in a statistically significant deterioration in CT and HCVA only. Five of 12 drivers also exhibited deterioration in LCVA, CT and RT. Little evidence emerged for deterioration in FIELDS and UFOV. Also, 7 of 12 drivers appeared to adjust their driving behaviour by reducing their speed on the driving simulator, leading to improved steering accuracy.

Conclusions: Pupillary dilation may lead to a decrease in vision and daylight driving performance in young people. A larger study, including a broader spectrum of subjects, is warranted before guidelines can be recommended.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Automobile Driving*
  • Contrast Sensitivity / drug effects
  • Female
  • Humans
  • Male
  • Mydriatics / adverse effects*
  • Tropicamide / adverse effects*
  • Vision Disorders / chemically induced*
  • Vision Tests / methods
  • Visual Acuity / drug effects

Substances

  • Mydriatics
  • Tropicamide