Changes in the surface potential of Lactobacillus acidophilus under freeze-thawing stress

Cryobiology. 2000 Aug;41(1):10-6. doi: 10.1006/cryo.2000.2259.

Abstract

The zeta potential of Lactobacillus acidophilus CRL 640, a measure of the net distribution of electrical charges on the bacterial surface, is a function of the glucose concentration in the growing media. With 2% glucose, cells in the stationary phase showed a zeta potential of -45 +/- 2 mV. With these cells, the zeta potential after freezing and thawing decreased to -32 +/- 2 mV and there was a decrease in viability. The changes in the surface potential correlated with damage to the cell surface as shown by electron microscopy. Freeze-thawed cells incubated in a rich medium recovered a zeta potential of -38 +/- 2 mV without cell growth. L. acidophilus CRL 640 showed the same value of surface potential as control cells when they were frozen and thawed in 2 M glycerol.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Membrane / drug effects
  • Cell Membrane / physiology
  • Cell Membrane / ultrastructure
  • Chemical Phenomena
  • Chemistry, Physical
  • Cryopreservation*
  • Cryoprotective Agents / pharmacology
  • Culture Media / pharmacology
  • Glucose / pharmacology
  • Glycerol / pharmacology
  • Lactobacillus acidophilus / drug effects
  • Lactobacillus acidophilus / physiology*
  • Lactobacillus acidophilus / ultrastructure
  • Membrane Potentials* / drug effects
  • Microscopy, Electron

Substances

  • Cryoprotective Agents
  • Culture Media
  • Glucose
  • Glycerol