Cluster of genes in Escherichia coli for ribosomal proteins, ribosomal RNA, and RNA polymerase subunits

Proc Natl Acad Sci U S A. 1975 Jul;72(7):2743-7. doi: 10.1073/pnas.72.7.2743.

Abstract

The transducing phage lambdarifd18 isolated by Kirschbaum and Konrad [(1973 J. Bacteriol. 116, 517-526] was found to carry structural genes for several 50S ribosomal proteins and 16S and 23S rRNA. It has previously been demonstrated [Kirschbaum & Scaife (1974) Mol. Gen. Genet. 132, 193-201] that this phage carries genes for the DNA-dependent RNA polymerase (nucleosidetriphosphate:RNA nucleotidyltransferase; EC 2.7.7.6) subunits beta and beta'. Thus, the region of the E. coli chromosome carried by lambdarifd18 contains a cluster of genes essential for transcription and translation.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Bacterial Proteins / biosynthesis
  • Coliphages / metabolism
  • DNA-Directed RNA Polymerases / biosynthesis*
  • Escherichia coli / metabolism*
  • Genes*
  • Leucine / metabolism
  • Methionine / metabolism
  • Peptide Fragments / analysis
  • Protein Biosynthesis
  • RNA, Bacterial / biosynthesis
  • RNA, Ribosomal / biosynthesis*
  • Ribosomal Proteins / biosynthesis*
  • Transcription, Genetic
  • Transduction, Genetic
  • Uracil / metabolism

Substances

  • Bacterial Proteins
  • Peptide Fragments
  • RNA, Bacterial
  • RNA, Ribosomal
  • Ribosomal Proteins
  • Uracil
  • Methionine
  • DNA-Directed RNA Polymerases
  • Leucine