Allogeneic transplantation of peripheral blood stem cells

Baillieres Best Pract Res Clin Haematol. 1999 Mar-Jun;12(1-2):261-78. doi: 10.1053/beha.1999.0022.

Abstract

Mobilized peripheral blood stem cells (PBSC) are increasingly being used instead of bone marrow for allogeneic transplantation. This chapter will briefly review important aspects of allogeneic PBSC transplantation including PBSC harvesting and donor safety, reconstitution of haematopoiesis and the immune system, graft-versus-host disease, graft-versus-leukaemia effects and graft engineering.

Publication types

  • Review

MeSH terms

  • Animals
  • Graft Survival
  • Graft vs Host Disease / etiology
  • Graft vs Leukemia Effect
  • Hematopoietic Stem Cell Mobilization / methods
  • Hematopoietic Stem Cell Mobilization / standards
  • Hematopoietic Stem Cell Transplantation / methods*
  • Hematopoietic Stem Cell Transplantation / standards
  • Humans
  • Leukapheresis / methods
  • Leukapheresis / standards
  • Transplantation, Homologous / methods
  • Transplantation, Homologous / standards