TMC-135A and B, new triene-ansamycins, produced by Streptomyces sp

MeSH terms

• Animals
• Antibiotics, Antineoplastic / chemistry*
• Antibiotics, Antineoplastic / isolation & purification
• Antibiotics, Antineoplastic / pharmacology*
• Drug Screening Assays, Antitumor
• Fermentation
• Humans
• Magnetic Resonance Spectroscopy
• Mice
• Molecular Structure
• Rifabutin / analogs & derivatives*
• Rifabutin / antagonists & inhibitors
• Rifabutin / chemistry
• Rifabutin / isolation & purification
• Rifabutin / pharmacology
• Streptomyces / classification
• Streptomyces / metabolism*
• Structure-Activity Relationship
• Tumor Cells, Cultured