Undecylenic acid inhibits morphogenesis of Candida albicans

Antimicrob Agents Chemother. 2000 Oct;44(10):2873-5. doi: 10.1128/AAC.44.10.2873-2875.2000.

Abstract

Resilient liners are frequently used to treat denture stomatitis, a condition often associated with Candida albicans infections. Of 10 liners tested, 2 were found to inhibit the switch from the yeast form to hyphae and a third was found to stimulate this switch. The inhibitor was determined to be undecylenic acid.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Candida albicans / drug effects*
  • Candida albicans / ultrastructure
  • Denture Liners / microbiology
  • Depression, Chemical
  • Humans
  • Morphogenesis
  • Undecylenic Acids / pharmacology*

Substances

  • Undecylenic Acids