Use of optically active cyclic N,N-dialkyl aminals in asymmetric induction

M E Jung; A Huang

doi:10.1021/ol0001517

Use of optically active cyclic N,N-dialkyl aminals in asymmetric induction

Org Lett. 2000 Aug 24;2(17):2659-61. doi: 10.1021/ol0001517.

Authors

M E Jung¹, A Huang

Affiliation

¹ Department of Chemistry and Biochemistry, University of California, Los Angeles 90095-1569, USA. jung@chem.ucla.edu

PMID: 10990421
DOI: 10.1021/ol0001517

Abstract

[reaction: see text]Cyclization of the optically active ketone N,N-dialkyl aminals A affords the diastereomer B as the major product with diastereoselectivities ranging from nearly 1:1 to essentially 100:0 depending on the cyclization studied.

Publication types

Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Aldehydes
Cyclization
Ketones / chemistry*
Stereoisomerism

Substances

Aldehydes
Ketones