Effects of pretransplant splenectomy and immunosuppression of humoral immunity in a pig-to-newborn goat cardiac xenograft model

Transplant Proc. 2000 Aug;32(5):1010-4. doi: 10.1016/s0041-1345(00)01088-5.

Authors

H Xu¹, S R Gundry, W W Hancock, C Zuppan, H Izutani, L L Bailey

Affiliation

¹ Departments of Surgery and Pathology, Loma Linda University Medical Center, Loma Linda, California, USA.

PMID: 10936324
DOI: 10.1016/s0041-1345(00)01088-5

No abstract available

MeSH terms

Animals
Animals, Newborn
Antibody Formation
CD2 Antigens / analysis
Endothelium, Vascular / pathology
Goats
Heart Transplantation / immunology*
Heart Transplantation / pathology
Hemorrhage
Immunosuppression Therapy / methods*
Killer Cells, Natural / immunology
Killer Cells, Natural / pathology
Methotrexate / pharmacology
Splenectomy*
Swine
Transplantation, Heterologous / immunology*
Transplantation, Heterologous / pathology
Tumor Necrosis Factor-alpha / analysis

Substances

CD2 Antigens
Tumor Necrosis Factor-alpha
Methotrexate