[Corticosteroid-induced epidural lipomatosis]

Rev Neurol (Paris). 2000 May;156(5):517-9.
[Article in French]

Abstract

Epidural lipomatosis is a rare disease, most often associated with chronic administration of exogenous steroids. We report the case of a 69-year-old man treated with 20mg prednisolone daily for 11 years because of polyarthritis. The patient complained of back pain associated with severe weakness of his lower limbs and brisk reflexes, with a progressive onset over one year. MRI showed epidural lipomatosis narrowing the epidural spaces from T-3 to T-10. Tapering of steroids was associated with slow but positive resolution of his symptoms.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Aged
  • Arthritis, Psoriatic / drug therapy*
  • Diagnosis, Differential
  • Epidural Space / drug effects
  • Epidural Space / pathology
  • Glucocorticoids / administration & dosage
  • Glucocorticoids / adverse effects*
  • Humans
  • Lipomatosis / chemically induced*
  • Lipomatosis / diagnosis
  • Magnetic Resonance Imaging
  • Male
  • Prednisolone / administration & dosage
  • Prednisolone / adverse effects*
  • Spinal Cord / drug effects
  • Spinal Cord / pathology
  • Spinal Cord Compression / chemically induced*
  • Spinal Cord Compression / diagnosis

Substances

  • Glucocorticoids
  • Prednisolone