[Chronopharmacologic approach to the administration of anticancer agents in pancreatic adenocarcinoma. Pilot experience]

C Focan; F Kreutz; D Focan-Henrard; N Moeneclaey; V Gillard; M Delforge; B Dallemagne; J Weerts; M T Closon; P Honoré

[Chronopharmacologic approach to the administration of anticancer agents in pancreatic adenocarcinoma. Pilot experience]

Rev Med Liege. 2000 Mar;55(3):149-53.

[Article in French]

Authors

C Focan¹, F Kreutz, D Focan-Henrard, N Moeneclaey, V Gillard, M Delforge, B Dallemagne, J Weerts, M T Closon, P Honoré

Affiliation

¹ Service d'Oncologie médicale, Les Cliniques Saint-Joseph, Liège.

PMID: 10823003

Abstract

The authors first analyzed the potential interest of the delivery of anticancer agents according to chronobiological concepts for human pancreatic cancer. They report their experience on 41 patients treated in adjuvant (12 cases) or palliative (29 cases) situations. The excellent therapeutic index observed warrants further evaluations of this concept in randomized trials.

Publication types

Clinical Trial
English Abstract

MeSH terms

Adenocarcinoma / drug therapy*
Adenocarcinoma / pathology
Adult
Aged
Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
Chemotherapy, Adjuvant
Chronotherapy*
Drug Administration Schedule
Female
Humans
Male
Middle Aged
Palliative Care
Pancreatic Neoplasms / drug therapy*
Pancreatic Neoplasms / pathology
Pilot Projects