Occurrence of aflatoxin M1 in Korean dairy products determined by ELISA and HPLC

Food Addit Contam. 2000 Jan;17(1):59-64. doi: 10.1080/026520300283595.

Abstract

The occurrence of aflatoxin M1 (AFM1) in pasteurized milk and dairy products was investigated by using direct competitive enzyme-linked immunosorbent assay (ELISA) and high-performance liquid chromatography (HPLC). The recoveries of AFM1 from the samples spiked at levels between 5 and 500 pg/ml were 88.0-106.5% for pasteurized milk and 84.0-94.0% for yoghurt by ELISA. By HPLC, the recoveries were 103-120% for pasteurized milk and 87.0-93.0% for yoghurt. The limits of detection were found to be 2 pg/ml by ELISA and 10 pg/ml by HPLC. Among a total of 180 samples collected in Seoul, Korea, the incidence of AFM1 in pasteurized milk, infant formula, powdered milk and yoghurt was 76, 85, 75, and 83%, respectively, with a mean concentration of 18, 46, 200, and 29 pg/g, respectively, when determined by ELISA. These results obtained by ELISA were closely related to those by HPLC for AFM1 (r2 = 0.9783).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aflatoxin M1 / analysis*
  • Animals
  • Chromatography, High Pressure Liquid
  • Enzyme-Linked Immunosorbent Assay
  • Food Contamination*
  • Infant Food / analysis
  • Korea
  • Milk / chemistry
  • Yogurt / analysis

Substances

  • Aflatoxin M1