[Patency study of internal mammary artery grafts: the usefulness of echo-enhancers for identifying the flow signal by color Doppler echocardiography]

Rev Esp Cardiol. 2000 Feb;53(2):189-93. doi: 10.1016/s0300-8932(00)75082-2.
[Article in Spanish]

Abstract

Objectives: a) To study the capacity of the technique of high-frequency color Doppler to detect flow signal of left internal mammary artery grafts; b) to assess the usefulness of an echo-enhancer agent to facilitate the detection of the signal, and c) to evaluate the patency of the graft according to its pulsed Doppler velocity profile pattern.

Methods: 39 consecutive patients were studied. A Hewlett-Packard 5500 echocardiograph was used, with a high-frequency probe (S12) applied at the high left parasternal border. When a graft signal was not elicited after a predetermined 5-minute check period, an intravenous dose of 4 g of Levovist (Schering España) at 400 mg/ml was administrated. According to previous studies, a pulsed Doppler flow profile with a predominantly diastolic pattern was considered a normal graft patency, while a systolic one was deemed as abnormal.

Results: Graft flow was identified by color Doppler in 33/39 patients (85%). The additional use of an echo-enhancer in 6 patients with no detected signal increased this proportion to 38/39 (97%). Normal flow patterns were seen in 34/38 (89%). Among the four patients with abnormal pattern, 1 case of early myocardial infarction was observed, while angiographic studies showed distal occlusion of the graft in 1 or the presence of competitive flow in 2 patients.

Conclusions: The high-frequency color Doppler technique allows the detection of a flow signal from internal mammary artery grafts in most patients. The administration of an echo-enhancer agent is useful in those with non detectable signals. An abnormal pulsed Doppler velocity pattern indicates graft malfunction.

Publication types

  • Clinical Trial

MeSH terms

  • Blood Flow Velocity
  • Contrast Media*
  • Echocardiography, Doppler, Color* / instrumentation
  • Echocardiography, Doppler, Color* / methods
  • Graft Occlusion, Vascular / diagnosis
  • Humans
  • Internal Mammary-Coronary Artery Anastomosis*
  • Magnetic Resonance Imaging
  • Mammary Arteries / diagnostic imaging*
  • Mammary Arteries / pathology
  • Mammary Arteries / physiopathology
  • Polysaccharides*
  • Prospective Studies
  • Vascular Patency*

Substances

  • Contrast Media
  • Polysaccharides
  • SHU 508