Keratosis lichenoides chronica: marked response to calcipotriol ointment

J Dermatol. 2000 Feb;27(2):123-6. doi: 10.1111/j.1346-8138.2000.tb02134.x.

Abstract

Keratosis lichenoides chronica (KCL) is a rare dermatosis characterized by a distinctive seborrheic dermatitis-like facial eruption, together with violaceous, papular, and nodular lesions on the extremities and trunk, typically arranged in a linear and reticulate pattern. KLC is resistant to therapy, although spontaneous remission has been reported. We describe a 35-year-old woman with KLC who had the typical features of widespread violaceous, reticulate, and striae-like eruptions with a prominent keratotic component over a nine-year period and who responded well to treatment with calcipotriol ointment. The immunohistochemical profiles are presented in addition to typical histopathologic features.

Publication types

  • Case Reports

MeSH terms

  • Administration, Cutaneous
  • Adult
  • Calcitriol / administration & dosage
  • Calcitriol / analogs & derivatives*
  • Calcitriol / therapeutic use
  • Chronic Disease
  • Dermatitis, Seborrheic / pathology
  • Dermatologic Agents / administration & dosage
  • Dermatologic Agents / therapeutic use*
  • Facial Dermatoses / pathology
  • Female
  • Humans
  • Keratosis / drug therapy*
  • Keratosis / pathology
  • Lichenoid Eruptions / drug therapy*
  • Lichenoid Eruptions / pathology
  • Ointments
  • Pigmentation Disorders / pathology
  • Remission, Spontaneous

Substances

  • Dermatologic Agents
  • Ointments
  • calcipotriene
  • Calcitriol