[Risk of serious acute asthma due to lupine flour associated with peanut allergy]

Rev Med Interne. 2000 Feb;21(2):191-4. doi: 10.1016/s0248-8663(00)88250-8.
[Article in French]

Abstract

Lupine flour (lupinus albus), recently authorized in France in human food, cross-reacts with peanuts. We report a case of acute asthma in a patient with allergy to peanuts.

Exegesis: This patient has a severe allergy to peanuts, presenting as acute asthma. Skin prick-tests to raw and cooked lupine flour were positive. The level of specific-IgE (Allerbio, France) to lupine flour were high. Oral challenge test induced acute asthma at a dose of 965 mg of lupine flour. This quantity may be included in 100 g of bread.

Conclusion: This case report points out the fact that lupine flour is a high-risk allergen in patients presenting allergy to peanuts. It is necessary to evaluate the allergenic risk of new foods before their introduction into human daily food intake and to establish a network of allergy vigilance.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adolescent
  • Arachis / adverse effects*
  • Asthma / chemically induced*
  • Asthma / immunology
  • Fabaceae / adverse effects*
  • Fabaceae / immunology
  • Female
  • Flour / adverse effects*
  • Food Hypersensitivity / complications*
  • Food Hypersensitivity / immunology
  • Humans
  • Immunoglobulin E / blood
  • Plants, Medicinal*
  • Skin Tests

Substances

  • Immunoglobulin E