The pseudomonas aeruginosa motR gene involved in regulation of bacterial motility

FEMS Microbiol Lett. 2000 Mar 1;184(1):57-62. doi: 10.1111/j.1574-6968.2000.tb08990.x.

Abstract

A mini-Tn5-Hg insertion mutant derived from Pseudomonas aeruginosa W51D (W51M1) was isolated in which mini-Tn5 insertion disrupted the motR gene showing that it forms part of the cluster involved in bacterial motility and chemotaxis. Characterization of the W51M1 motility behavior, and also of a PAO1 motR::mini-Tn5-Hg mutant, suggests that the product of the motR gene is a negative regulator of bacterial motility which controls the number of flagella per cell.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Bacterial Proteins / genetics*
  • Bacterial Proteins / physiology
  • Base Sequence
  • Chemotaxis / genetics
  • Chemotaxis / physiology
  • DNA Transposable Elements / genetics
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / genetics
  • Molecular Sequence Data
  • Movement / physiology
  • Mutagenesis, Insertional
  • Mutation
  • Operon
  • Pseudomonas aeruginosa / genetics*
  • Pseudomonas aeruginosa / physiology
  • Sequence Analysis, DNA
  • Sigma Factor / genetics

Substances

  • Bacterial Proteins
  • DNA Transposable Elements
  • DNA, Bacterial
  • FliA protein, Bacteria
  • MotR protein, Pseudomonas aeruginosa
  • Sigma Factor

Associated data

  • GENBANK/AF052586