Hepatopulmonary syndrome after allogeneic bone marrow transplantation

Bone Marrow Transplant. 1999 Dec;24(11):1249-52. doi: 10.1038/sj.bmt.1702056.

Abstract

A 10-year-old girl with aplastic anemia received an allogeneic bone marrow transplantation (BMT). Three years after an uneventful course apart from chronic graft-versus-host disease (GVHD) she presented with chronic hypoxemia, reduced diffusion capacity of the lungs, normal spirometric lung function and increased bilirubin and liver enzymes. Intrapulmonary vascular dilatations were demonstrated. Pulmonary complications after BMT may include a hepatopulmonary syndrome (liver disease, hypoxemia, intrapulmonary vascular dilatations).

Publication types

  • Case Reports

MeSH terms

  • Anemia, Aplastic / therapy
  • Bone Marrow Transplantation / adverse effects*
  • Child
  • Dilatation, Pathologic / etiology
  • Female
  • Graft vs Host Disease
  • Hepatopulmonary Syndrome / etiology*
  • Humans
  • Hypoxia / etiology
  • Pulmonary Circulation
  • Transplantation, Homologous / adverse effects