Abstract
Pantoprazole is a proton pump inhibitor which has recently had its clinical license extended to include maintenance therapy for the treatment of reflux oesophagitis, Helicobacter pylori eradication and short-term intravenous administration. This article reviews the history of gastric acid secretion and examines the role of proton pump inhibitors, particularly pantoprazole, in the treatment of acid-related disorders.
Publication types
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Historical Article
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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2-Pyridinylmethylsulfinylbenzimidazoles
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Anti-Ulcer Agents / therapeutic use*
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Benzimidazoles / therapeutic use*
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Drug Interactions
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Female
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Gastric Acid / metabolism*
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Gastric Juice / chemistry
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History, 18th Century
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History, 19th Century
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History, 20th Century
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Humans
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Omeprazole / analogs & derivatives
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Pantoprazole
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Peptic Ulcer / drug therapy*
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Pregnancy
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Proton Pump Inhibitors*
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Sulfoxides / therapeutic use*
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Treatment Outcome
Substances
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2-Pyridinylmethylsulfinylbenzimidazoles
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Anti-Ulcer Agents
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Benzimidazoles
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Proton Pump Inhibitors
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Sulfoxides
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Pantoprazole
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Omeprazole