Glomerulonephritis in a neonate with atypical congenital lupus and toxoplasmosis

Pediatr Nephrol. 1999 Nov;13(9):850-3. doi: 10.1007/s004670050714.

Abstract

The development of glomerulonephritis as a complication of neonatal lupus or congenital toxoplasmosis is extremely rare. We report a case of membranous glomerulonephritis occurring in a neonate with toxoplasmosis and atypical congenital lupus, including high-titer antinuclear antibodies and hypocomplementemia. This case illustrates that glomerulonephritis in the neonate may be induced by passively transferred maternal antibodies.

Publication types

  • Case Reports

MeSH terms

  • Basement Membrane / pathology
  • Basement Membrane / ultrastructure
  • Female
  • Glomerular Mesangium / pathology
  • Glomerular Mesangium / ultrastructure
  • Glomerulonephritis / complications*
  • Glomerulonephritis / pathology
  • Humans
  • Infant, Newborn
  • Lupus Erythematosus, Systemic / complications*
  • Lupus Erythematosus, Systemic / congenital
  • Male
  • Microscopy, Electron
  • Microscopy, Fluorescence
  • Pregnancy
  • Toxoplasmosis, Congenital / complications*