[Preoperative staging of pancreatic adenocarcinoma: a practice survey of French gastroenterologists and digestive surgeons. Ordering of supplemental examinations and preoperative criteria of loco-regional spread]

Gastroenterol Clin Biol. 1999 Oct;23(10):1055-61.
[Article in French]

Abstract

Background: Means used by physicians to perform preoperative staging of pancreatic adenocarcinoma are not well known. Therapeutic strategy used relies on knowledge of loco-regional spread criteria.

Aims: To assess the frequency of prescription of imaging procedures in patients with suspected pancreatic head adenocarcinoma; the use by French gastroenterologists (GE) and digestive surgeons (S) of criteria which lead to suspect lymph node invasion or vascular involvement; the frequency of histological determination in patients with unresectable tumor; if there is a difference between GE and S.

Methods: All the French GE (n = 3466) and S (n = 687) were sent a survey asking them about their habits.

Results: 615 answers were received (GE = 426, S = 189). There was no significant difference between GE and S for the prescription of ultrasonography and CT scan. Endosonography and upper digestive endoscopy were more systematically performed by GE than S (44 vs 35% and 50 vs 35%, respectively). Celio-mesenteric angiography was less often used by GE (6 vs 13%). Laparoscopy was electively used by 35% GE and 52% S. None of vascular involvement criteria was used by more than 75% of GE and S. Tumor-vessel interface loss was used by 46% GE and 16% S (P < 0.001). Intravascular thrombosis and truncular portal hypertension signs were used more often by S than GE (84 vs. 71%: P < 0.001; 65 vs. 51%: P < 0.001). None of nodal involvement criteria was used by more than 50% of physicians. All these nodal criteria were used more often by GE than S (P < 0.001). Percentage of physicians requiring histological confirmation in case of unresectable tumor was 41%.

Conclusion: Preoperative staging of suspected pancreatic head adenocarcinoma is performed with grossly the same manner by GE and S. Histological proof is searched for in a low percentage of cases. Imaging criteria of loco-regional spread of pancreatic adenocarcinoma are heterogeneously used by GE and S, the former using them more frequently than the latter. A better use of imaging criteria is necessary to optimise the treatment of patients with pancreatic adenocarcinoma.

Publication types

  • Comparative Study
  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenocarcinoma / diagnosis
  • Adenocarcinoma / pathology*
  • Adenocarcinoma / surgery
  • Angiography
  • Biopsy
  • Data Interpretation, Statistical
  • Endosonography
  • Gastroenterology*
  • General Surgery*
  • Humans
  • Laparoscopy
  • Lymphatic Metastasis
  • Neoplasm Staging
  • Pancreas / pathology
  • Pancreatic Neoplasms / diagnosis
  • Pancreatic Neoplasms / pathology*
  • Pancreatic Neoplasms / surgery
  • Preoperative Care
  • Surveys and Questionnaires
  • Tomography, X-Ray Computed