[Percutaneous ethanol injection therapy with hepatic arterial infusion chemotherapy for liver metastases from gastric cancer]

Gan To Kagaku Ryoho. 1999 Oct;26(12):1772-6.
[Article in Japanese]

Abstract

Ten patients with liver metastases from advanced gastric cancer received percutaneous ethanol injection therapy (PEI) and chemotherapy by hepatic arterial infusion (HAI) via implantable reservoir. A 90% ethanol solution including 10%. Lipiodol was injected in the liver as PEI.5-FU, EPIR and MMC were used as the regimen for HAI chemotherapy. We have performed this therapy (PEI + HAI) for ten patients with liver metastases since February, 1997. These patients have received this therapy for 4-36 months and three patients died within 16 months. However, three patients did not develop any liver failure after this therapy. The median survival rate was 25.2 months. There are statistically significant differences between upto ss and over se of invasion, and between INF alpha and gamma (p = 0.005).

Publication types

  • English Abstract

MeSH terms

  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
  • Epirubicin / administration & dosage
  • Ethanol / administration & dosage*
  • Fluorouracil / administration & dosage
  • Hepatic Artery
  • Humans
  • Infusion Pumps, Implantable*
  • Infusions, Intra-Arterial
  • Injections, Intralesional
  • Iodized Oil / administration & dosage
  • Liver Neoplasms / drug therapy*
  • Liver Neoplasms / mortality
  • Liver Neoplasms / secondary*
  • Male
  • Middle Aged
  • Mitomycin / administration & dosage
  • Stomach Neoplasms / pathology*
  • Survival Rate

Substances

  • Ethanol
  • Epirubicin
  • Mitomycin
  • Iodized Oil
  • Fluorouracil

Supplementary concepts

  • FEM protocol