To guarantee the supply of accurate clinical information, the laboratory system uses external quality control, internal quality control, and data checking method. The correlation among these laboratory items and the continuity of the inter-subject variation are applied to self-acting assessment of data. In this text, we introduce other insights, not yet generalized to date, to guarantee the accuracy. First, we emphasize the importance of accurate data communication and redundancy of composition in the information equipment to improve the reliability of information transaction. Secondly, we applied the data checking system which synchronizes with pathophysiological changes in the patients to the diagnosis support system using the hypothesis deduction method. Thirdly, we present the mobility presumption method in the seat of protein electrophoresis crimp as a suitable example to obtain more accurate information processing of the original data.