CD30 positive (non-anaplastic) peripheral T-cell lymphoma of the thyroid gland

Haematologica. 1999 Oct;84(10):946-8.

Abstract

Primary non-Hodgkin's lymphoma of the thyroid gland are infrequent tumors. They almost exclusively derive from B cells of mucosa-associated lymphatic tissue and only a very small minority of them is represented by T cell lymphomas. CD30 molecule, other than in Hodgkin's and Redd-Sternberg' cells, is strictly associated with anaplastic large cell lymphoma and ALK lymphomas, the latter being identified by the monoclonal antibody ALK1. We report a case of CD30-positive non-anaplastic (ALK1-negative) peripheral T cell lymphoma of the thyroid gland and speculate on aspects concerning diagnosis and the morphologic and immunohistochemical findings.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cell Size
  • Female
  • Humans
  • Immunohistochemistry
  • Ki-1 Antigen / analysis*
  • Lymphoma, T-Cell, Peripheral / diagnosis
  • Lymphoma, T-Cell, Peripheral / immunology*
  • Thyroid Neoplasms / diagnosis
  • Thyroid Neoplasms / immunology*

Substances

  • Ki-1 Antigen