Microtubule cytoskeleton: No longer an also Ran

Curr Biol. 1999 Sep 23;9(18):R704-7. doi: 10.1016/s0960-9822(99)80445-x.

Abstract

The Ran GTPase cycle has been extensively studied in the context of nuclear transport. Recent work indicates that this GTPase cycle also plays an important role in regulating the microtubule cytoskeleton.

Publication types

  • Review

MeSH terms

  • Animals
  • Centrosome / physiology
  • Centrosome / ultrastructure
  • Chromatin / physiology
  • Guanosine Triphosphate / physiology
  • Humans
  • Microtubules / physiology*
  • Microtubules / ultrastructure
  • Models, Biological
  • Morphogenesis
  • Multigene Family
  • Oocytes
  • Spindle Apparatus / physiology
  • Spindle Apparatus / ultrastructure
  • Xenopus laevis
  • ran GTP-Binding Protein / genetics
  • ran GTP-Binding Protein / physiology*

Substances

  • Chromatin
  • Guanosine Triphosphate
  • ran GTP-Binding Protein