Left ventricular hypertrophy, treadmill tests, and 24-hour blood pressure in pediatric transplant patients

Kidney Int. 1999 Oct;56(4):1566-70. doi: 10.1046/j.1523-1755.1999.00667.x.

Abstract

Background: Hypertension and left ventricular hypertrophy (LVH) are possible complications in pediatric patients after renal transplantation.

Methods: We performed left ventricular echocardiography, 24-hour ambulatory blood pressure monitoring (24-hr ABPM), and treadmill tests in 28 pediatric renal transplant patients (mean age 16.1 +/- 3.7; time since transplantation 36 +/- 23 months). Left ventricular mass (LVM) was indexed for height 2.7.

Results: LVH was found in 82% of the patients. Seven of these patients were normotensive by 24-hour ABPM, but five patients showed a hypertensive systolic BP response during the treadmill test. LVM/height 2.7 correlated significantly with the mean 24-hour systolic BP (P = 0.002) and with the maximal exercise systolic BP (P = 0.002).

Conclusion: LVH is frequent in pediatric renal transplant patients. More information is needed with respect to the risk for LVH, including data from 24-hour ABPM and treadmill testing.

Publication types

  • Clinical Trial

MeSH terms

  • Adolescent
  • Adult
  • Blood Pressure
  • Blood Pressure Monitoring, Ambulatory*
  • Child
  • Echocardiography
  • Exercise Test
  • Female
  • Humans
  • Hypertrophy, Left Ventricular / complications*
  • Hypertrophy, Left Ventricular / diagnostic imaging*
  • Kidney Failure, Chronic / complications*
  • Kidney Transplantation*
  • Male
  • Postoperative Complications / diagnostic imaging