Histologic studies of the effects of circulating hot saline on the uterus before hysterectomy

J Am Assoc Gynecol Laparosc. 1999 Aug;6(3):269-73. doi: 10.1016/s1074-3804(99)80059-0.

Abstract

Study objective: To evaluate a new device for endometrial ablation.

Design: (Canadian Task Force classification II-1).

Setting: University-affiliated hospital.

Patients: Thirty-two women scheduled for hysterectomy.

Interventions: Endometrial ablation and hysterectomy.

Measurements and main results: The new device for endometrial ablation was evaluated by studying depth of necrosis after staining for the oxidative enzyme NADH. Uniform endomyometrial necrosis was achieved at a depth of 2 to 4 mm with 90 degrees C saline circulated for 10 minutes.

Conclusion: The procedure was successful in all patients, and there were no adverse clinical sequelae. (J Am Assoc Gynecol Laparosc 6(3):269-273, 1999)

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Electrocoagulation / methods
  • Endometrium / pathology*
  • Endometrium / surgery*
  • Female
  • Hot Temperature*
  • Humans
  • Hysterectomy / methods*
  • Hysteroscopy / methods
  • Preoperative Care
  • Sensitivity and Specificity
  • Sodium Chloride / administration & dosage*
  • Uterine Hemorrhage / surgery*

Substances

  • Sodium Chloride