The main predictors of outcome after infarction (exercise capacity, ejection fraction, and extent of jeopardized myocardium) can all be identified using stress echocardiography. This review addresses the place of stress echocardiography in postinfarct risk evaluation, relative to clinical evaluation, and other technologies. The test is accurate for identification of multivessel disease and for predicting outcomes, is versatile, and can be used early after infarction.