The double bond in unsaturated fatty acids is the necessary and sufficient requirement for the inhibition of expression of endothelial leukocyte adhesion molecules through interference with nuclear factor-kappaB activation

Lipids. 1999:34 Suppl:S213-4. doi: 10.1007/BF02562293.
No abstract available

MeSH terms

  • Cell Adhesion / drug effects
  • Cell Adhesion / physiology
  • Cells, Cultured
  • Endothelium, Vascular / drug effects
  • Endothelium, Vascular / physiology*
  • Fatty Acids, Unsaturated / chemistry
  • Fatty Acids, Unsaturated / pharmacology*
  • Gene Expression Regulation / drug effects*
  • Humans
  • Intercellular Adhesion Molecule-1 / genetics*
  • Lipopolysaccharides / pharmacology
  • NF-kappa B / metabolism*
  • Oleic Acid / chemistry
  • Oleic Acid / pharmacology*
  • RNA, Messenger / genetics
  • Tetradecanoylphorbol Acetate / pharmacology
  • Transcription, Genetic / drug effects
  • Umbilical Veins
  • Vascular Cell Adhesion Molecule-1 / genetics*

Substances

  • Fatty Acids, Unsaturated
  • Lipopolysaccharides
  • NF-kappa B
  • RNA, Messenger
  • Vascular Cell Adhesion Molecule-1
  • Intercellular Adhesion Molecule-1
  • Oleic Acid
  • Tetradecanoylphorbol Acetate