[Aggressive therapy and combination therapy in severe hyperlipidemia]

Abstract

In cases of severe hyperlipidemia, we have very effective therapeutic tools nowadays. LDL-apheresis is still the most effective therapy for familial hypercholesterolemia, especially in its homocygous form. In combination with statins, LDL-cholesterol can be lowered by 80%. Most other genetic and secondary hyperlipidemias can effectively be treated by lipid lowering drugs. This aggressive treatment gains more and more on importance in view of the tough recommendations of specific scientific societies. Atorvastatin and simvastatin can lower LDL-cholesterol by 60%. In this report different therapies and combination therapies for hyperlipidemia are discussed.