Comparative FISH-mapping of six expressed gene loci to river buffalo and sheep chromosomes

Cytogenet Cell Genet. 1999;84(3-4):161-3. doi: 10.1159/000015246.

Abstract

Six expressed gene loci (NF1, CRYB1, CHRNB1, TP53, P4HB and GH1), recently assigned to cattle chromosome 19 by both radiation hybrid analysis and FISH-mapping, were comparatively FISH-mapped to river buffalo chromosome (BBU) 3p and sheep chromosome (OAR) 11, extending the physical map in these two important bovids. The six loci mapped to the same homoeologous chromosome bands of BBU 3p and OAR 11, and their gene order was centromere-NF1-CRYB1-CHNRB1-TP53-(GH1, P4HB).

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Animals, Domestic / genetics
  • Buffaloes / genetics*
  • Centromere / genetics
  • Chromosome Banding
  • Chromosomes / genetics*
  • DNA Probes
  • Genes / genetics*
  • In Situ Hybridization, Fluorescence*
  • Physical Chromosome Mapping*
  • Sheep / genetics*

Substances

  • DNA Probes