O6-benzylguanine-resistant mutant MGMT genes improve hematopoietic cell tolerance to alkylating agents

Prog Exp Tumor Res. 1999:36:65-81. doi: 10.1159/000061986.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Alkylating Agents / pharmacology*
  • Drug Resistance / genetics
  • Enzyme Inhibitors / pharmacology*
  • Guanine / analogs & derivatives*
  • Guanine / pharmacology
  • Hematopoietic Stem Cells / drug effects*
  • Humans
  • O(6)-Methylguanine-DNA Methyltransferase / genetics*

Substances

  • Alkylating Agents
  • Enzyme Inhibitors
  • O(6)-benzylguanine
  • Guanine
  • O(6)-Methylguanine-DNA Methyltransferase