Co-receptors on B lymphocytes

Curr Opin Immunol. 1999 Jun;11(3):249-55. doi: 10.1016/s0952-7915(99)80041-7.

Abstract

Co-receptors have been shown to regulate the antigen-receptor signaling threshold for B cell responses by modulating the activation of signaling molecules that are essential for transmitting a signal through the antigen-receptor. Co-receptors appear to modulate the signaling threshold for B cell tolerance distinctly from that for B cell activation.

Publication types

  • Review

MeSH terms

  • Animals
  • Antigens, CD / metabolism
  • Antigens, CD19 / metabolism
  • Antigens, Differentiation, B-Lymphocyte / metabolism
  • B-Lymphocytes / immunology*
  • Cell Adhesion Molecules*
  • Humans
  • Immune Tolerance
  • Lectins*
  • Lymphocyte Activation
  • Phosphoric Monoester Hydrolases / metabolism
  • Receptors, Antigen, B-Cell / metabolism*
  • Receptors, Complement 3d / metabolism
  • Receptors, IgG / metabolism
  • Sialic Acid Binding Ig-like Lectin 2
  • Signal Transduction / immunology

Substances

  • Antigens, CD
  • Antigens, CD19
  • Antigens, Differentiation, B-Lymphocyte
  • CD22 protein, human
  • CD72 protein, human
  • Cell Adhesion Molecules
  • Lectins
  • Receptors, Antigen, B-Cell
  • Receptors, Complement 3d
  • Receptors, IgG
  • Sialic Acid Binding Ig-like Lectin 2
  • Phosphoric Monoester Hydrolases