Spontaneous intralesional haemorrhage in dysembryoplastic neuroepithelial tumours: a series of five cases

J Neurol Neurosurg Psychiatry. 1999 Jul;67(1):97-101. doi: 10.1136/jnnp.67.1.97.

Abstract

Five patients with dysembryoplastic neuroepithelial tumour (DNT) showing extensive secondary haemorrhage, a finding not previously associated with these neoplasms, are described. The clinical presentations, neuroimaging findings, and histopathological features of these patients are reviewed. One patient, a previously asymptomatic 12 year old girl, presented with an acute intracerebral haemorrhage into a DNT. A further four young adults with histories of intractable partial and generalised seizures dating from childhood showed significant chronic haemorrhages within DNT, the MRI appearances in one patient giving a false impression of a cavernoma. Histopathology disclosed vascular abnormalities within these tumours which, together with other factors discussed, may have predisposed these tumours to haemorrhage.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brain Neoplasms / pathology
  • Brain Neoplasms / physiopathology*
  • Brain Neoplasms / surgery
  • Child
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Neoplasms, Germ Cell and Embryonal / pathology
  • Neoplasms, Germ Cell and Embryonal / physiopathology*
  • Neoplasms, Neuroepithelial / pathology
  • Neoplasms, Neuroepithelial / physiopathology*