[Simplified electroretinography protocol and diagnosis of retinal dystrophies in children]

J Fr Ophtalmol. 1999 Apr;22(3):383-7.
[Article in French]

Abstract

Purpose: To report results of a simplified electroretinogram in children.

Patients: 124 children under 6 years of age with nystagmus, blindness, neurological disease, cone rod dystrophy in the family, or abnormal fundus appearance were examined.

Method: The electroretinogram was recorded by corneal electrodes in an awake state without sedation. A light-emitting orange diode stimulator was used. Stimulation was performed subsequently after 3 minutes of light adaptation and after 8 minutes of darkness. If the electroretinogram was abnormal, a second recording was done a few weeks later using the same method. In some cases, the children were re-examined, and a ganzfeld stimulation ERG was recorded.

Results and discussion: This method allowed a reliable diagnosis of photoreceptor dystrophy: Leber's congenital amaurosis with or without rare metabolic diseases, X link pigmentary retinopathy or retinal dystrophy with general disease in children. It helped to differentiate isolated retinal pigment changes with normal electroretinogram from functional retinal impairment and rod-cone dystrophy from other retinal dystrophies.

Publication types

  • English Abstract

MeSH terms

  • Adaptation, Ocular
  • Age Factors
  • Child
  • Child, Preschool
  • Clinical Protocols
  • Electroretinography / instrumentation
  • Electroretinography / methods*
  • Humans
  • Infant
  • Reproducibility of Results
  • Retinal Degeneration / classification
  • Retinal Degeneration / diagnosis*
  • Retinal Degeneration / etiology
  • Retinal Degeneration / physiopathology
  • Retrospective Studies
  • Time Factors