Abstract
Crystal structures have been solved for two bacterial outer membrane proteins, FhuA and FepA, which mediate active transport of chelated iron. Analysis of ligand-induced changes in the structure of FhuA has provided our first structural insights into an active transport mechanism for a complex solute.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Bacterial Outer Membrane Proteins / chemistry*
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Bacterial Outer Membrane Proteins / metabolism
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Biological Transport
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Carrier Proteins / chemistry
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Carrier Proteins / metabolism
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Crystallography, X-Ray
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Escherichia coli / chemistry*
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Escherichia coli / metabolism
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Escherichia coli Proteins*
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Receptors, Cell Surface*
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Receptors, Virus / chemistry
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Receptors, Virus / metabolism
Substances
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Bacterial Outer Membrane Proteins
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Carrier Proteins
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Escherichia coli Proteins
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FhuA protein, E coli
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Receptors, Cell Surface
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Receptors, Virus
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enterobactin receptor