FTY720, a novel immunosuppressant, prolongs rat skin allograft survival by decreasing T-cell infiltration into grafts

Transplant Proc. 1999 Feb-Mar;31(1-2):1227-9. doi: 10.1016/s0041-1345(98)01974-5.
No abstract available

MeSH terms

  • Animals
  • CD8-Positive T-Lymphocytes / immunology
  • Fingolimod Hydrochloride
  • Immunosuppressive Agents / therapeutic use*
  • Lymphocyte Activation
  • Male
  • Propylene Glycols / therapeutic use*
  • Rats
  • Rats, Inbred F344
  • Rats, Inbred Strains
  • Receptors, Interleukin-2 / analysis
  • Skin Transplantation / immunology*
  • Skin Transplantation / pathology
  • Sphingosine / analogs & derivatives
  • T-Lymphocyte Subsets / immunology
  • T-Lymphocytes / drug effects
  • T-Lymphocytes / immunology*
  • T-Lymphocytes / pathology
  • Transplantation, Homologous
  • Transplantation, Isogeneic

Substances

  • Immunosuppressive Agents
  • Propylene Glycols
  • Receptors, Interleukin-2
  • Fingolimod Hydrochloride
  • Sphingosine