Tetrahydrobenzindoles: selective antagonists of the 5-HT7 receptor

J Med Chem. 1999 Feb 25;42(4):533-5. doi: 10.1021/jm980519u.
No abstract available

MeSH terms

  • Animals
  • COS Cells
  • Cerebral Cortex / metabolism
  • Guinea Pigs
  • Humans
  • In Vitro Techniques
  • Indoles / chemical synthesis*
  • Indoles / chemistry
  • Indoles / metabolism
  • Neostriatum / metabolism
  • Pyridines / chemical synthesis*
  • Pyridines / chemistry
  • Pyridines / metabolism
  • Radioligand Assay
  • Rats
  • Receptors, Serotonin / metabolism*
  • Recombinant Proteins / metabolism
  • Serotonin Antagonists / chemical synthesis*
  • Serotonin Antagonists / chemistry
  • Serotonin Antagonists / metabolism

Substances

  • 2a-(4-phenyl-1,2,3,6-tetrahydropyridyl)cyclohex(a-3,4)indole-2-one
  • Indoles
  • Pyridines
  • Receptors, Serotonin
  • Recombinant Proteins
  • Serotonin Antagonists
  • serotonin 7 receptor